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Applications of Tetrahydropyrrole
1. Pharmaceutical Intermediates
Tetrahydropyrrole is widely used in the pharmaceutical field as an intermediate in the synthesis of various drugs. For example, it is an essential intermediate in the synthesis of antidepressants, antianxiety drugs, and certain cardiovascular drugs. Its unique ring structure provides specific chemical reaction sites, enabling the efficient synthesis of drug molecules.
SN | English Name | Chinese Name | Drug efficacy |
1 | Buflomedil | 丁咯地爾 | Cerebrovascular disease medications |
2 | Dextromoramide tartrate | 酒石酸右嗎拉胺 | Analgesics |
3 | Procyclidine HCI | 丙環(huán)定,普環(huán)定,卡馬特靈 | Antiparkinsonian medications |
4 | Piromidic acid | 吡咯米酸 | Anti-infective medications |
5 | Amixetrine | 阿米西群 | Antispasmodics |
6 | Bepridil | 芐普地爾 | |
7 | Prolintane | 普羅林坦,丙苯乙吡咯 | Stimulants and antidepressants |
8 | Pyrrocaine | 吡咯卡因 | Local anesthetics |
It can also be used as a solvent. For example, tetrahydropyrrole was used as a solvent in the semi-synthesis of the cardiovascular drug simvastatin, with a molar consumption ratio of approximately 1:1.
2. Pesticide Synthesis
In the pesticide field, tetrahydropyrrole is also widely used in the synthesis of various insecticides and herbicides. Its use as an intermediate not only improves the synthesis efficiency of pesticides but also enhances their stability and biological activity, such as Lolopgranule.
3. New Materials Research and Development
The application of tetrahydropyrrole in new materials is also gaining attention. For example, in the synthesis of polymers with unique optical properties, tetrahydropyrrole can serve as a crosslinker or functional monomer, imparting excellent properties to the materials.
4. Catalyst Promoter
In chemical production, tetrahydropyrrole is often used as a catalyst promoter, significantly improving the efficiency and selectivity of catalytic reactions. In particular, in complex chemical reactions, tetrahydropyrrole can effectively reduce reaction temperature and pressure, thereby reducing production costs.
Applications of Tetrahydropyrrole
1. Pharmaceutical Intermediates
Tetrahydropyrrole is widely used in the pharmaceutical field as an intermediate in the synthesis of various drugs. For example, it is an essential intermediate in the synthesis of antidepressants, antianxiety drugs, and certain cardiovascular drugs. Its unique ring structure provides specific chemical reaction sites, enabling the efficient synthesis of drug molecules.
SN | English Name | Chinese Name | Drug efficacy |
1 | Buflomedil | 丁咯地爾 | Cerebrovascular disease medications |
2 | Dextromoramide tartrate | 酒石酸右嗎拉胺 | Analgesics |
3 | Procyclidine HCI | 丙環(huán)定,普環(huán)定,卡馬特靈 | Antiparkinsonian medications |
4 | Piromidic acid | 吡咯米酸 | Anti-infective medications |
5 | Amixetrine | 阿米西群 | Antispasmodics |
6 | Bepridil | 芐普地爾 | |
7 | Prolintane | 普羅林坦,丙苯乙吡咯 | Stimulants and antidepressants |
8 | Pyrrocaine | 吡咯卡因 | Local anesthetics |
It can also be used as a solvent. For example, tetrahydropyrrole was used as a solvent in the semi-synthesis of the cardiovascular drug simvastatin, with a molar consumption ratio of approximately 1:1.
2. Pesticide Synthesis
In the pesticide field, tetrahydropyrrole is also widely used in the synthesis of various insecticides and herbicides. Its use as an intermediate not only improves the synthesis efficiency of pesticides but also enhances their stability and biological activity, such as Lolopgranule.
3. New Materials Research and Development
The application of tetrahydropyrrole in new materials is also gaining attention. For example, in the synthesis of polymers with unique optical properties, tetrahydropyrrole can serve as a crosslinker or functional monomer, imparting excellent properties to the materials.
4. Catalyst Promoter
In chemical production, tetrahydropyrrole is often used as a catalyst promoter, significantly improving the efficiency and selectivity of catalytic reactions. In particular, in complex chemical reactions, tetrahydropyrrole can effectively reduce reaction temperature and pressure, thereby reducing production costs.
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